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Approved Use

Repatha^® is an injectable prescription medicine used:

to reduce the risk of major adverse cardiovascular (CV) events, READ MOREsuch as death from cardiovascular disease, heart attack, stroke, certain types of chest pain conditions (unstable angina) requiring hospitalization, or certain types of heart surgery, in adults at increased risk for these events.
to reduce the risk of major adverse cardiovascular (CV) events, such as death from cardiovascular disease, heart attack, stroke, certain types of chest pain conditions (unstable angina) requiring hospitalization, or certain types of heart surgery, in adults at increased risk for these events.
Along with diet and exercise to reduce low-density lipoprotein (LDL) or bad cholesterol in adults with high blood cholesterol levels called hypercholesterolemia and in adults with a type of high cholesterol called heterozygous familial hypercholesterolemia (HeFH).

Repatha^® is an injectable prescription medicine used:

to reduce the risk of major adverse READ MORE cardiovascular (CV) events, such as death from cardiovascular disease, heart attack, stroke, certain types of chest pain conditions (unstable angina) requiring hospitalization, or certain types of heart surgery, in adults at increased risk for these events.
Along with diet and exercise to reduce low-density lipoprotein (LDL) or bad cholesterol in adults with high blood cholesterol levels called hypercholesterolemia and in adults with a type of high cholesterol called heterozygous familial hypercholesterolemia (HeFH).

For adults with increased risk of a major cardiovascular event

With LDL-C (bad cholesterol), lower is better.
Here’s why.

LDL-C stands for low-density lipoprotein cholesterol. It’s often called “bad” cholesterol, because too much LDL-C causes plaque buildup, which is associated with an increased risk of a serious cardiovascular event, like a heart attack or stroke.

There are many reasons why someone could have high LDL-C. Inactivity, an unhealthy diet, or even genetic makeup or family history may make it more difficult for someone to remove or break down bad cholesterol.

High LDL-C also doesn’t have any physical symptoms. As a result, elevated LDL-C levels may go undetected. But patients can lower their LDL-C. In fact, LDL-C is one of the most important modifiable risk factors for reducing the risk of another heart attack or stroke.

Normal Artery

Clear blood flow

Cholesterol-Rich Plaque Building in Artery

Plaque blocks blood flow

LDL-C delivers cholesterol into artery walls, forming fatty deposits known as plaque.

Plaque rupture can create clogs and make it difficult for blood to flow through your body.

Sometimes the clogs can block blood flow, leading to a heart attack or stroke. And since those clogs are caused by high LDL-C, the lower your LDL-C, the lower your risk.

High LDL-C and Diabetes

Even if you feel fine, high LDL-C is a leading risk factor for a heart attack and stroke. If you have diabetes, you're twice as likely to have a cardiovascular event compared to those without diabetes.

This makes getting your LDL-C below goal even more important.

How Is High LDL-C Treated?

Diet improvements and increased exercise can help lower bad cholesterol, but they may not always be enough.

If lifestyle changes aren't getting you below goal, an LDL cholesterol-lowering medication like Repatha^® could help.

Want to learn more?
Check out some cardiovascular disease organizations dedicated to patient education, advocacy, and more.

American Heart Association
American Heart Association
The American Heart Association (AHA) is dedicated to fighting heart disease and stroke. Their mission is to improve the lives of all Americans by providing public health education in a variety of ways. Check out their website for heart disease education and support, and tips for healthy living, like their “Life’s Simple 7”—7 small steps to big changes to better living.

CardioSmart American College of Cardiology Foundation
CardioSmart American College of Cardiology Foundation
CardioSmart is the patient education and empowerment initiative brought to you by the American College of Cardiology. Their mission is to help patients treat, and manage their cardiovascular disease.

Family Heart Foundation
Family Heart Foundation
The Family Heart Foundation focuses on timely identification and improved care of familial hypercholesterolemia (FH). Through research, advocacy, and education, they drive change and empower families to navigate their own health.

Family Heart Foundation
The FH Foundation
The Family Heart Foundation focuses on timely identification and improved care of familial hypercholesterolemia (FH). Through research, advocacy, and education, they drive change and empower families to navigate their own health.

Mended Hearts
Mended Hearts
Mended Hearts is a national and community-based nonprofit organization that has been offering the gift of hope to heart disease patients, their families, and caregivers. Mended Hearts provides a variety of programs, including, local support, available over the phone or in person.

WomenHeart Foundation
WomenHeart Foundation
WomenHeart is a national coalition for women with heart disease with a focus on early detection, accurate diagnosis, and proper treatment. WomenHeart’s mission is to improve the health and quality of life of women living with or at risk of heart disease, and to advocate for their benefit.

These third party websites may contain helpful resources and are provided for your information only. Amgen does not endorse and is not responsible for the content included in these websites or any associated resources.

Important Safety Information

Do not use Repatha^® if you are allergic to evolocumab or to any of the ingredients in Repatha^®.

Before you start using Repatha^®, tell your healthcare provider about all your medical conditions, including if you are allergic to rubber or latex, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Repatha^® is available as prefilled single-dose SureClick^® autoinjectors and prefilled single-dose syringes that either contain dry natural rubber (a derivative of latex) in the needle cover or are not made with natural rubber latex. The carton and “Instructions for Use" in the carton will state if your prefilled single-dose SureClick^® autoinjector or prefilled single-dose syringe contains dry natural rubber. The single-dose Pushtronex^® system (on-body infusor with prefilled cartridge) is not made with natural rubber latex.

Tell your healthcare provider or pharmacist about any prescription and over-the-counter medicines, vitamins, or herbal supplements you take.

What are the possible side effects of Repatha^®?

Repatha^® can cause serious side effects including serious allergic reactions. Stop taking Repatha^® and call your healthcare provider or seek emergency help right away if you have any of these symptoms: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.

The most common side effects of Repatha^® include: runny nose, sore throat, symptoms of the common cold, flu or flu-like symptoms, back pain, high blood sugar levels (diabetes) and redness, pain, or bruising at the injection site.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Repatha^®. Ask your healthcare provider or pharmacist for more information. Call your healthcare provider for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

APPROVED USE

What is Repatha^®?

Repatha^® is an injectable prescription medicine used:

to reduce the risk of major adverse cardiovascular (CV) events, such as death from cardiovascular disease, heart attack, stroke, certain types of chest pain conditions (unstable angina) requiring hospitalization, or certain types of heart surgery, in adults at increased risk for these events.
Along with diet and exercise to reduce low-density lipoprotein (LDL) or bad cholesterol in adults with high blood cholesterol levels called hypercholesterolemia and in adults with a type of high cholesterol called heterozygous familial hypercholesterolemia (HeFH).

Please see full Prescribing Information, including Patient Product Information.

IMPORTANT SAFETY INFORMATION

Do not use Repatha^® if you are allergic to evolocumab or to any of the ingredients in Repatha^®.

Before you start using Repatha^®, tell your healthcare provider about all your medical conditions, including if you are allergic to rubber or latex,

if you are allergic to rubber or latex, are pregnant or plan to become pregnant, or are breastfeeding or plan

Use your Repatha® (evolocumab) Co-Pay Card Today To Pay as Little as $25 for a 1-month supply or $50 for a 3-month supply.*

With LDL-C (bad cholesterol), lower is better. Here’s why.

Important Safety Information

APPROVED USE

Use your Repatha^® (evolocumab) Co-Pay Card
Today To Pay as Little as $25 for a 1-month
supply or $50 for a 3-month supply.*

With LDL-C (bad cholesterol), lower is better.
Here’s why.