Single-dose prefilled autoinjector†
15-second at-home self-injection with hand-held device
‡Injection under the skin.
Take Once a Month
Single-dose on-body infusor with prefilled cartridge§
5-minute at-home self-injection with hands-free device
§420 mg/3.5 mL.
**Injection under the skin.
Yes. Make sure your Repatha® is in its original box and clearly labeled. Learn more about how to store Repatha®.
Check your transportation provider’s policy for needles. If flying, bring a copy of your prescription or a doctor’s note to show airport security.
Repatha® must be used within 30 days if kept at room temperature (68°F to 77°F) in its original box.
Put the used autoinjector/orange needle cap OR the Pushtronex® in an FDA-cleared sharps-disposal container right away after use. Do not throw away (dispose of) the autoinjector/orange cap OR the Pushtronex® in your household trash. If you do not have an FDA-cleared sharps-disposal container, you may use a household container that is made of a heavy-duty plastic; can be closed with a tight-fitting, puncture-resistant lid, without sharps being able to come out; upright and stable during use; leak-resistant; and properly labeled to warn of hazardous waste inside the container.2
When your sharps-disposal container is almost full, you will need to follow your community guidelines for the right way to dispose of your sharps-disposal container. There may be state or local laws about how you should throw away used needles and syringes. For more information about safe sharps disposal, and for specific information about sharps disposal in the state that you live in, go to the FDA’s website at www.fda.gov/safesharpsdisposal.2
It’s best to store Repatha® in the refrigerator (36°F to 46°F), but Repatha® can be stored at room temperature (up to 77°F) for up to 30 days in its original box.
In the event of a temporary room temperature exposure (up to 77°F), Repatha® may be returned to the refrigerator (36°F to 46°F) for the duration of its shelf life.
If you left Repatha® out at room temperature for more than 30 days, discard Repatha®. If you think the room temperature went above 77°F, call 1-844-REPATHA (1-844-737-2842) to learn more.
You must wait for at least 30 minutes after removing the autoinjector from the refrigerator prior to injecting yourself to ensure all of the medication is administered and to minimize discomfort.
Reminder: Do not remove the needle shield/cap from the autoinjector until you are ready to inject.2
Do not use Repatha® if you are allergic to evolocumab or to any of the ingredients in Repatha®.
Before you start using Repatha®, tell your healthcare provider about all your medical conditions, including if you are allergic to rubber or latex, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. The needle covers on the single-dose prefilled syringes and the inside of the needle caps on the single-dose prefilled SureClick® autoinjectors contain dry natural rubber. The single-dose Pushtronex® system (on-body infusor with prefilled cartridge) is not made with natural rubber latex.
Tell your healthcare provider or pharmacist about any prescription and over-the-counter medicines, vitamins, or herbal supplements you take.
What are the possible side effects of Repatha®?
Repatha® can cause serious side effects including serious allergic reactions. Stop taking Repatha® and call your healthcare provider or seek emergency help right away if you have any of these symptoms: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.
The most common side effects of Repatha® include: runny nose, sore throat, symptoms of the common cold, flu or flu-like symptoms, back pain, high blood sugar levels (diabetes) and redness, pain, or bruising at the injection site.
Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of Repatha®. Ask your healthcare provider or pharmacist for more information. Call your healthcare provider for medical advice about side effects.
What is Repatha®?
Repatha® is an injectable prescription medicine used:
Please see full Prescribing Information.