Repatha^® is a breakthrough medicine that can help you dramatically
lower bad cholesterol and reduce your risk of heart attack.

Repatha^® Works Differently From a Statin

Statins help stop your liver from making as much cholesterol
Repatha^® helps your liver clear bad cholesterol by limiting the actions of a protein called PCSK9, which means less bad cholesterol in your blood

See How Repatha^® Works Differently

Up to 90% of people

dramatically lowered

their bad cholesterol with

Repatha^® plus a statin
to 70 mg/dL or below at 48 weeks.

In just 1 month,

Repatha^® brings bad

cholesterol down.
It works fast.
Patients lowered bad cholesterol by an average of 63% in just 3 months.

Repatha^® plus a statin is

proven to reduce

your chance of

heart attack by 27%.
In a study, patients not treated with Repatha^® had more heart attacks (4.6%) compared to those treated with Repatha^® (3.4%).

See How Repatha^®
Works Differently

Maybe you’re taking a statin, swapping steaks for salads, and power walking through the neighborhood. And even though you're doing your best, you're still struggling to lower your bad cholesterol.

Take a look at this video that explains bad cholesterol and how to get yours down with Repatha^®.

Repatha^® and HeFH

For people with inherited high bad cholesterol (familial hypercholesterolemia, or FH) who still need to lower their bad cholesterol with diet alone or together with other cholesterol-lowering medicines.

For some people, diet, weight, or physical activity level might not be the primary cause of high LDL. Sometimes high LDL is caused by an inherited condition called FH.

Heterozygous FH (HeFH) represents one form of this common genetic disorder that affects the liver's ability to remove excess LDL. HeFH is an inherited condition, which means it is caused by one or more abnormal genes that can be passed down from one or both parents. This can lead to premature cardiovascular disease, as well as other complications caused by high LDL.

Repatha^® + a statin lowered LDL around 60%.*
Repatha^® drives LDL down in people with HeFH.

*Results from a study at week 12 compared to a statin. Some patients were also on other cholesterol-lowering therapies. Repatha^® was taken every 2 weeks or once monthly. Your results may vary.

Important Safety Information

Do not use Repatha^® if you are allergic to evolocumab or to any of the ingredients in Repatha^®.

Before you start using Repatha^®, tell your healthcare provider about all your medical conditions, including if you are allergic to rubber or latex, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. The needle covers on the single-dose prefilled syringes and the inside of the needle caps on the single-dose prefilled SureClick^® autoinjectors contain dry natural rubber. The single-dose Pushtronex^® system (on-body infusor with prefilled cartridge) is not made with natural rubber latex.

Tell your healthcare provider or pharmacist about any prescription and over-the-counter medicines, vitamins, or herbal supplements you take.

What are the possible side effects of Repatha^®?

Repatha^® can cause serious side effects including, serious allergic reactions. Stop taking Repatha^® and call your healthcare provider or seek emergency help right away if you have any of these symptoms: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.

The most common side effects of Repatha^® include: runny nose, sore throat, symptoms of the common cold, flu or flu-like symptoms, back pain, high blood sugar levels (diabetes), and redness, pain, or bruising at the injection site.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Repatha^®. Ask your healthcare provider or pharmacist for more information. Call your healthcare provider for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see full Prescribing Information.