Approved Use

Repatha® is an injectable prescription medicine used:

  • in adults with cardiovascular disease to reduce the risk of heart attack, stroke, and certain types of heart surgery. READ MORE
  • along with diet alone or together with other cholesterol-lowering medicines in adults with high blood cholesterol levels called primary hyperlipidemia (including a type of high cholesterol called heterozygous familial hypercholesterolemia) to reduce low-density lipoprotein (LDL) or bad cholesterol.

How to 
Take 
Repatha®

Repatha® is available in three injection options. Learn more about each Repatha® dosing option below and the support available to assist you.

Take Every Two Weeks

SureClick® Autoinjector

Single-use prefilled autoinjector*

15-second at-home self-injection with hand-held device

  • Audible click when you start and finish your dose
  • Hidden needle
  • Can inject into your stomach or thigh, or inject into your arm if assisted
  • No need for syringes or vials
  • Download and read instructions before using
  Watch the demo video

*140 mg/mL   Injection under the skin

Take Once a Month

Pushtronex® System

Single-use on-body infusor with prefilled cartridge

9-minute at-home self-injection with hands-free device

  • Lights and sounds when you start and finish your dose
  • Hidden needle
  • Can inject into your stomach or thigh, or inject into your arm if assisted
  • Can do moderate physical activities, such as walking, reaching, or bending, during injection
  • Fits in the palm of your hand
  • Download and read instructions before using
  Watch the demo video

420 mg/3.5mL   Injection under the skin

Prefilled Syringe§

A single-use prefilled syringe is also available. Watch the injection demonstration video below to learn how to use it.

  Watch the demo video

§140 mg/mL

INJECTION 
SUPPORT

36°F - 46°F
68°F - 77°F

Storing and traveling with Repatha®

Store Repatha® in the refrigerator (36°F to 46°F) until you’re ready to use it. Repatha® can also be stored at room temperature (68°F to 77°F) in its original box for up to 30 days. This makes it easier to take your medicine with you when you’re on the go.

Talk to a RepathaReady® Nurse

RepathaReady® nurses are here to help. Do you have a question about Repatha® or need injection support? Call us. Nurse support is available in other languages, including Spanish.

RepathaReady® nurses are available 7 days a week by phone at 1-844-REPATHA (1-844-737-2842), 9 AM–11 PM ET.

Call Us

Medication reminders

Would you like a reminder when it’s time to inject Repatha® or refill your prescription?

Sign up for Reminders

Get a Needle Disposal Container

Needle-disposal containers can be mailed to your door, so you can recycle your used needles safely, conveniently, and at no cost to you.

Call Us

Important Safety Information

Do not use Repatha® if you are allergic to evolocumab or to any of the ingredients in Repatha®.

Before you start using Repatha®, tell your healthcare provider about all your medical conditions, including if you are allergic to rubber or latex, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. The needle covers on the single-use prefilled syringes and the inside of the needle caps on the single-use prefilled SureClick® autoinjectors contain dry natural rubber. The single-use Pushtronex® system (on-body infusor with prefilled cartridge) is not made with natural rubber latex.

Tell your healthcare provider or pharmacist about any prescription and over-the-counter medicines, vitamins, or herbal supplements you take.

What are the possible side effects of Repatha®?

Repatha® can cause serious side effects including, serious allergic reactions. Stop taking Repatha® and call your healthcare provider or seek emergency help right away if you have any of these symptoms: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.

The most common side effects of Repatha® include: runny nose, sore throat, symptoms of the common cold, flu or flu-like symptoms, back pain, high blood sugar levels (diabetes), and redness, pain, or bruising at the injection site.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Repatha®. Ask your healthcare provider or pharmacist for more information. Call your healthcare provider for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see full Prescribing Information.

Important Safety Information

Do not use Repatha® if you are allergic to evolocumab or to any of the ingredients in Repatha®.

Before you start using Repatha®, tell your healthcare provider about all your medical conditions, including if you are allergic to rubber or latex, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. The needle covers on the single-use prefilled syringes and the inside of the needle caps on the single-use prefilled SureClick® autoinjectors contain dry natural rubber. The single-use Pushtronex® system (on-body infusor with prefilled cartridge) is not made with natural rubber latex.

Tell your healthcare provider or pharmacist about any prescription and over-the-counter medicines, vitamins, or herbal supplements you take.

What are the possible side effects of Repatha®?

Repatha® can cause serious side effects including, serious allergic reactions. Stop taking Repatha® and call your healthcare provider or seek emergency help right away if you have any of these symptoms: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.

The most common side effects of Repatha® include: runny nose, sore throat, symptoms of the common cold, flu or flu-like symptoms, back pain, high blood sugar levels (diabetes), and redness, pain, or bruising at the injection site.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Repatha®. Ask your healthcare provider or pharmacist for more information. Call your healthcare provider for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see full Prescribing Information.

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