Approved Use

Repatha® is an injectable prescription medicine used:

  • to reduce the risk of major adverse cardiovascular (CV) events, READ MOREsuch as death from cardiovascular disease, heart attack, stroke, certain types of chest pain conditions (unstable angina) requiring hospitalization, or certain types of heart surgery, in adults at increased risk for these events.
  • to reduce the risk of major adverse cardiovascular (CV) events, such as death from cardiovascular disease, heart attack, stroke, certain types of chest pain conditions (unstable angina) requiring hospitalization, or certain types of heart surgery, in adults at increased risk for these events.
  • Along with diet and exercise to reduce low-density lipoprotein (LDL) or bad cholesterol in adults with high blood cholesterol levels called hypercholesterolemia and in adults with a type of high cholesterol called heterozygous familial hypercholesterolemia (HeFH).

Repatha® is an injectable prescription medicine used:

  • to reduce the risk of major adverse READ MORE cardiovascular (CV) events, such as death from cardiovascular disease, heart attack, stroke, certain types of chest pain conditions (unstable angina) requiring hospitalization, or certain types of heart surgery, in adults at increased risk for these events.
  • Along with diet and exercise to reduce low-density lipoprotein (LDL) or bad cholesterol in adults with high blood cholesterol levels called hypercholesterolemia and in adults with a type of high cholesterol called heterozygous familial hypercholesterolemia (HeFH).
Congratulations!
You’ve updated your selections.
Congratulations—You Are Now Enrolled in Amgen® SupportPlus!

Use your Repatha® (evolocumab) Co-Pay Card
Today To Pay as Little as $25 for a 1-month
supply or $50 for a 3-month supply.*

You are now enrolled based on your selected insurance type.†

To use your co-pay card, follow these 3 simple steps

Print, Screenshot or save co-pay card information shown on this page or in your confirmation email
Share your co-pay card Information with your pharmacist
Pick up your Repatha® prescription

This is your personal co-pay card information:

If you have any questions, please contact 1-844-REPATHA (1-844-737-2842).

*Eligibility criteria and program maximums apply. Please see full Terms and Conditions.

*Eligibility criteria and program maximums apply. Please see full repatha.com/copaytcs.

†Further verification will be completed at the time the card is used to confirm that you are an eligible commercially insured patient.

You can now view your current selection in your
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Repatha® (evolocumab) Injection 140mg/mL Logo Linking to Homepage

Dear Repatha® Patient,

We want to let you know about an upcoming change to Repatha®.

  • The Repatha® 140 mg/mL prefilled single-dose syringe will be discontinued effective Q1 2026.
  • If you are currently using the Repatha® prefilled single-dose syringe, we kindly ask that you contact your healthcare provider to transition to the Repatha® 140 mg/mL prefilled single-dose SureClick® Autoinjector (shown below).
  • The Repatha® SureClick® Autoinjector delivers the same medicine and dose — only the device is changing.

This is not a recall. There are no safety or quality concerns with your current Repatha® prefilled single-dose syringe. The decision to discontinue this device was made to uphold the high standards Amgen has for patient experience. We are committed to support patients’ transition to the Repatha® SureClick autoinjector.

Prefilled single-dose syringe

syrgine
The Repatha® prefilled single-dose syringe will be discontinued effective Q1 2026.
140 mg/mL prefilled
single-dose syringe
(NDC 72511-501-01)

SureClick® Autoinjector- Active and Available

Injection.png
Talk to your Doctor about transitioning to the Repatha® SureClick® Autoinjector
Repatha® 140 mg/mL
prefilled single-dose SureClick® Autoinjector (NDC 72511-393-02)

If you’re currently using the Repatha® prefilled single-dose syringe:

Next Steps & Support Available to You

It is important to note that there are no concerns about the drug product quality, efficacy, or patient safety of the Repatha® devices

What You Can Do:

  • Contact your doctor before your next refill to request a prescription to transition to the Repatha® SureClick® Autoinjector.
  • Continue your current dosing schedule unless directed otherwise.
  • For help with using the new device, visit www.repatha.com/injection to learn more about how to take Repatha®, review Instructions for Use, and view a Demo Video along with other helpful resources.

We’re here to support your journey. We provide support for patients currently using the prefilled single-dose syringe and who are transitioning to the SureClick Autoinjector through Amgen SupportPlus® by calling 1-844-REPATHA (1-844-737-2842) and selecting prompt number 2, Monday – Friday 8:00 AM – 8:00 PM ET.

Other Questions?

If you have any additional questions about Repatha®, or need assistance with injection training, please call your healthcare provider.

For a Spanish translation of this update, please visit www.RepathaEspanol.com/ActualizacionJeringaPrecargada.

Sincerely,
Amgen Inc.

Important Safety Information

Do not use Repatha® if you are allergic to evolocumab or to any of the ingredients in Repatha®.

Before you start using Repatha®, tell your healthcare provider about all your medical conditions, including if you are allergic to rubber or latex, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Repatha® is available as prefilled single-dose SureClick® autoinjectors and prefilled single-dose syringes that either contain dry natural rubber (a derivative of latex) in the needle cover or are not made with natural rubber latex. The carton and “Instructions for Use" will state if your prefilled single-dose SureClick® autoinjector or prefilled single-dose syringe contains dry natural rubber. The single-dose Pushtronex® system (on-body infusor with prefilled cartridge) is not made with natural rubber latex.

Tell your healthcare provider or pharmacist about any prescription and over-the-counter medicines, vitamins, or herbal supplements you take.

What are the possible side effects of Repatha®?

Repatha® can cause serious side effects including serious allergic reactions. Stop taking Repatha® and call your healthcare provider or seek emergency help right away if you have any of these symptoms: trouble breathing or swallowing, raised bumps (hives), rash or itching, swelling of the face, lips, tongue, throat or arms.

The most common side effects of Repatha® include: runny nose, sore throat, symptoms of the common cold, flu or flu-like symptoms, back pain, high blood sugar levels (diabetes) and redness, pain, or bruising at the injection site.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Repatha®. Ask your healthcare provider or pharmacist for more information. Call your healthcare provider for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

APPROVED USE

What is Repatha®?

Repatha® is an injectable prescription medicine used:

  • to reduce the risk of major adverse cardiovascular (CV) events, such as death from cardiovascular disease, heart attack, stroke, certain types of chest pain conditions (unstable angina) requiring hospitalization, or certain types of heart surgery, in adults at increased risk for these events.
  • Along with diet and exercise to reduce low-density lipoprotein (LDL) or bad cholesterol in adults with high blood cholesterol levels called hypercholesterolemia and in adults with a type of high cholesterol called heterozygous familial hypercholesterolemia (HeFH).

Please see full Prescribing Information, including Patient Product Information.

IMPORTANT SAFETY INFORMATION

Do not use Repatha® if you are allergic to evolocumab or to any of the ingredients in Repatha®.

Before you start using Repatha®, tell your healthcare provider about all your medical conditions, including if you are allergic to rubber or latex,


if you are allergic to rubber or latex, are pregnant or plan to become pregnant, or are breastfeeding or plan