Repatha® works differently than a statin

Different types of treatments are used to lower high LDL (bad cholesterol). Statins are the most commonly prescribed treatments.
Your doctor may decide you need additional help in lowering your LDL and prescribe Repatha®.
Repatha® works differently than statins to lower LDL. The following is a brief overview of how Repatha® and statins work.

What is Repatha®

  • An injectable medicine that is an antibody
  • Repatha® helps the liver clear LDL by limiting the actions of PCSK9
    • Less PCSK9 means less LDL in your blood

What are statins

  • Statins block a specific enzyme that causes less cholesterol, including LDL, to be made. They also increase the liver’s ability to break down cholesterol that’s already in your blood.

Taken together, Repatha® + a
statin is proven to dramatically lower LDL

See how Repatha® drives down LDL in people with plaque-related heart or blood vessel problems or inherited high LDL (HeFH).

The effect of Repatha® on heart problems, such as heart attacks, stroke, or death, has not been determined.

Getting started on Repatha®?

Watch a video that shows you how to take it

Ask your doctor if Repatha® can
get you on the path to even lower LDL

Use this discussion guide to get the most
out of your next office visit.

Download the guide

Questions about
paying for Repatha®?

Pay no more than $5* with the Repatha® Copay Card, and learn about other financial programs

*Eligibility Requirements for Repatha® Copay Card: Program is available to patients with commercial insurance and applies to deductible, coinsurance, and copay for Repatha®. This program is not open to patients receiving prescription reimbursement under any federal, state or government-funded healthcare program, such as Medicare, Medicare Advantage, Medicare Part D, Medicaid, Medigap, Veterans Affairs (VA), the Department of Defense (DoD) or TRICARE® or where prohibited by law.

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Important Safety Information and Approved Use

Do not use Repatha® if you are allergic to evolocumab or to any of the ingredients in Repatha®.

Before you start using Repatha®, tell your healthcare provider about all your medical conditions, including allergies, and if you are allergic to rubber or latex, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. The needle covers on the single-use prefilled syringes and the inside of the needle caps on the single-use prefilled SureClick® autoinjectors contain dry natural rubber. The single-use Pushtronex system (on-body infusor with prefilled cartridge) is not made with natural rubber latex.

Tell your healthcare provider or pharmacist about any prescription and over-the-counter medicines you are taking or plan to take, including natural or herbal remedies.

What are the possible side effects of Repatha®?

Repatha® may cause allergic reactions. Call your healthcare provider or go to the nearest hospital emergency room right away if you have any symptoms of an allergic reaction including a severe rash, redness, severe itching, a swollen face, or trouble breathing.

The most common side effects of Repatha® include: runny nose, sore throat, symptoms of the common cold, flu or flu-like symptoms, back pain, and redness, pain, or bruising at the injection site.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Repatha®. Ask your healthcare provider or pharmacist for more information. Call your healthcare provider for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-10881-800-FDA-1088.

Approved Use

Repatha® is an injectable prescription medicine called a PCSK9 inhibitor. Repatha® is used:

  • along with diet and maximally tolerated statin therapy in adults with heterozygous familial hypercholesterolemia (an inherited condition that causes high levels of LDL) or atherosclerotic heart or blood vessel problems, who need additional lowering of LDL cholesterol.

The effect of Repatha® on heart problems, such as heart attacks, stroke, or death, has not been determined.

Please see full Prescribing Information on this website.

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